Influence of interstitial cells of cajal in congenital ureteropelvic junction obstruction

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Changes in Structure, Interstitial Cajal-like Cells and Apoptosis of Smooth Muscle Cells in Congenital Ureteropelvic Junction Obstruction

OBJECTIVE The goal of this study is to evaluate some structural changes in muscular, collagenous and neural components as well as expression of Cajal-like cells and apoptosis of smooth muscle cells in congenital ureteropelvic junction obstruction (UPJO). METHODS Tissue specimens were obtained from 25 patients with UPJO and compared with normal ureteropelvic junction regions of 19 autopsies. I...

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Renal osteodystrophy secondary to congenital bilateral ureteropelvic junction obstruction.

A 4-year-old girl presented with progressive distension of the abdomen and bowing of the legs (genu valgum) since birth. She was anemic, with a blood pressure of 180/110 mmHg. The serum level of creatinine was 1.7 mg/dL. She had hypocalcemia, and elevated serum level of phosphorous and parathyroid hormones. Ultrasonography revealed bilateral grossly hydronephrotic kidneys with thinned out paren...

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Results of Pyeloplasty in patients with Ureteropelvic Junction Obstruction in Pediatric Surgery Center in Bandar Abbas

Introduction: Ureteropelvic junction obstruction (UPJO) is associated with inadequate urine drainage from renal pelvis into ureter. UPJO results from incomplete recanalization of proximal ureter during fetal period which finally leads to hydrostatic distention of renal pelvis and calyces. Diagnosis is based on clinical symptoms, ultrasound, and diuretic isotopic renogram. Various surgical metho...

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Congenital Ureteropelvic Junction Stenosis

Introduction Congenital ureteropelvic junction (UPJ) stenosis is a disturbance in the flow of urine at the crossover point from the kidney pelvis to the ureter, with a dilatated and obstructed renal-pelvic calyceal system (Figure 89.1). UPJ obstruction is the most frequent congenital malformation of the genitourinary system. Its incidence is around 1 out of 1,000 newborns. The first sonographic...

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Delayed maturation of interstitial cells of Cajal in meconium obstruction.

BACKGROUND/PURPOSE The etiology of meconium obstruction without cystic fibrosis is unclear. Interstitial cells of Cajal (ICC) function as pacemakers in gut motility and may play a role in the pathophysiology of the disease. METHODS The ICC were examined by immunohistochemical staining with anti-c-kit antibody in the bowel walls of 6 neonates who had meconium obstruction without cystic fibrosi...

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ژورنال

عنوان ژورنال: Journal of Indian Association of Pediatric Surgeons

سال: 2020

ISSN: 0971-9261

DOI: 10.4103/jiaps.jiaps_115_19